Cardiac Denervation Affects Exercise Training-Induced Improvements in Cardiorespiratory Fitness of Heart Transpant Patients: 1766 Board #1 June 2, 1: 00 PM - 3: 00 PM.

s were prepared by the authors and printed as submitted. T H U R S D A Y, JU N E 2, 2016 was carried out in the third group (DM-EX group) for four weeks. The animals were sacrificed; the blood were collected; the blood glucose was measured; the autophagy relationship proteins (i.e., Atg5, LC3-I, LC3-II, Atg12) and apoptosis proteins (i.e., Beclin1, caspase3, cleaved caspase3, Bcl2, P-Bcl2) were analysis by western blot. The results show that the level of blood glucose was higher in DM and DM-EX groups than in control group (p <0.05). EX decreased the level of blood glucose in DM group (p <0.05). The levels of LC3-I, LC3-II were higher in DM and DM-EX group than in control group (p <0.05). The ratio of LC3-II and LC3-I was highest in DM group than in other group (p <0.05). The Atg5, Atg12 and Bcl2 were highest in DM-EX group than in others (p <0.05). The Beclin1 and P-Bcl2 were higher in DM-EX group than in control group (p <0.05). Those results suggested that EX may affect muscle autophagy from DM damage through Bcl2, Atg5, and Atg12 increasing. 1769 Board #4 June 2, 1:00 PM 3:00 PM Effect of Exercise on Pulmonary Arterial Capacitance